In midfield Arsène needs to find someone to replace Mikel Arteta at the base of our midfield. Mathieu Flamini and Calum Chambers are the most likely choices. If Per Mertesacker is not ready or if Koscielny is rested due to a persistent achilles problem then that choice gets removed. Mesut Özil could return to the team if ready and that could see the side switch back to a 4-2-3-1. Would Wilshere be the one to miss out? or would Arsène risk asking Ramsey and Wilshere to share that responsibility?